Cross-level Contrastive Learning and Consistency Constraint for Semi-supervised Medical Image Segmentation

Semi-supervised learning (SSL), which aims at leveraging a few labeled images and a large number of unlabeled images for network training, is beneficial for relieving the burden of data annotation in medical image segmentation. According to the experience of medical imaging experts, local attributes such as texture, luster and smoothness are very important factors for identifying target objects like lesions and polyps in medical images. Motivated by this, we propose a cross-level contrastive learning scheme to enhance representation capacity for local features in semi-supervised medical image segmentation. Compared to existing image-wise, patch-wise and point-wise contrastive learning algorithms, our devised method is capable of exploring more complex similarity cues, namely the relational characteristics between global and local patch-wise representations. Additionally, for fully making use of cross-level semantic relations, we devise a novel consistency constraint that compares the predictions of patches against those of the full image. With the help of the cross-level contrastive learning and consistency constraint, the unlabelled data can be effectively explored to improve segmentation performance on two medical image datasets for polyp and skin lesion segmentation respectively. Code of our approach is available.

Deep Transformers for Fast Small Intestine Grounding in Capsule Endoscope Video

Capsule endoscopy is an evolutional technique for examining and diagnosing intractable gastrointestinal diseases. Because of the huge amount of data, analyzing capsule endoscope videos is very time-consuming and labor-intensive for gastrointestinal medicalists. The development of intelligent long video analysis algorithms for regional positioning and analysis of capsule endoscopic video is therefore essential to reduce the workload of clinicians and assist in improving the accuracy of disease diagnosis. In this paper, we propose a deep model to ground shooting range of small intestine from a capsule endoscope video which has duration of tens of hours. This is the first attempt to attack the small intestine grounding task using deep neural network method. We model the task as a 3-way classification problem, in which every video frame is categorized into esophagus/stomach, small intestine or colorectum. To explore long-range temporal dependency, a transformer module is built to fuse features of multiple neighboring frames. Based on the classification model, we devise an efficient search algorithm to efficiently locate the starting and ending shooting boundaries of the small intestine. Without searching the small intestine exhaustively in the full video, our method is implemented via iteratively separating the video segment along the direction to the target boundary in the middle. We collect 113 videos from a local hospital to validate our method. In the 5-fold cross validation, the average IoU between the small intestine segments located by our method and the ground-truths annotated by broad-certificated gastroenterologists reaches 0.945.