Large-vocabulary forensic pathological analyses via prototypical cross-modal contrastive learning

Forensic pathology is critical in determining the cause and manner of death through post-mortem examinations, both macroscopic and microscopic. The field, however, grapples with issues such as outcome variability, laborious processes, and a scarcity of trained professionals. This paper presents SongCi, an innovative visual-language model (VLM) designed specifically for forensic pathology. SongCi utilizes advanced prototypical cross-modal self-supervised contrastive learning to enhance the accuracy, efficiency, and generalizability of forensic analyses. It was pre-trained and evaluated on a comprehensive multi-center dataset, which includes over 16 million high-resolution image patches, 2,228 vision-language pairs of post-mortem whole slide images (WSIs), and corresponding gross key findings, along with 471 distinct diagnostic outcomes. Our findings indicate that SongCi surpasses existing multi-modal AI models in many forensic pathology tasks, performs comparably to experienced forensic pathologists and significantly better than less experienced ones, and provides detailed multi-modal explainability, offering critical assistance in forensic investigations. To the best of our knowledge, SongCi is the first VLM specifically developed for forensic pathological analysis and the first large-vocabulary computational pathology (CPath) model that directly processes gigapixel WSIs in forensic science.

Jointly Sparse Signal Recovery and Support Recovery via Deep Learning with Applications in MIMO-based Grant-Free Random Access

In this paper, we investigate jointly sparse signal recovery and jointly sparse support recovery in Multiple Measurement Vector (MMV) models for complex signals, which arise in many applications in communications and signal processing. Recent key applications include channel estimation and device activity detection in MIMO-based grant-free random access which is proposed to support massive machine-type communications (mMTC) for Internet of Things (IoT). Utilizing techniques in compressive sensing, optimization and deep learning, we propose two model-driven approaches, based on the standard auto-encoder structure for real numbers. One is to jointly design the common measurement matrix and jointly sparse signal recovery method, and the other aims to jointly design the common measurement matrix and jointly sparse support recovery method. The proposed model-driven approaches can effectively utilize features of sparsity patterns in designing common measurement matrices and adjusting model-driven decoders, and can greatly benefit from the underlying state-of-the-art recovery methods with theoretical guarantee. Hence, the obtained common measurement matrices and recovery methods can significantly outperform the underlying advanced recovery methods. We conduct extensive numerical results on channel estimation and device activity detection in MIMO-based grant-free random access. The numerical results show that the proposed approaches provide pilot sequences and channel estimation or device activity detection methods which can achieve higher estimation or detection accuracy with shorter computation time than existing ones. Furthermore, the numerical results explain how such gains are achieved via the proposed approaches.