Magnetic Milli-spinner for Robotic Endovascular Surgery

Vascular diseases such as thrombosis, atherosclerosis, and aneurysm, which can lead to blockage of blood flow or blood vessel rupture, are common and life-threatening. Conventional minimally invasive treatments utilize catheters, or long tubes, to guide small devices or therapeutic agents to targeted regions for intervention. Unfortunately, catheters suffer from difficult and unreliable navigation in narrow, winding vessels such as those found in the brain. Magnetically actuated untethered robots, which have been extensively explored as an alternative, are promising for navigation in complex vasculatures and vascular disease treatments. Most current robots, however, cannot swim against high flows or are inadequate in treating certain conditions. Here, we introduce a multifunctional and magnetically actuated milli-spinner robot for rapid navigation and performance of various treatments in complicated vasculatures. The milli-spinner, with a unique hollow structure including helical fins and slits for propulsion, generates a distinct flow field upon spinning. The milli-spinner is the fastest-ever untethered magnetic robot for movement in tubular environments, easily achieving speeds of 23 cm/s, demonstrating promise as an untethered medical device for effective navigation in blood vessels and robotic treatment of numerous vascular diseases.

Spinning-enabled Wireless Amphibious Origami Millirobot

Wireless millimeter-scale origami robots that can locomote in narrow spaces and morph their shapes have recently been explored with great potential for biomedical applications. Existing millimeter-scale origami devices usually require separate geometrical components for locomotion and functions, which increases the complexity of the robotic systems and their operation upon limited locomotion modes. Additionally, none of them can achieve both on-ground and in-water locomotion. Here we report a magnetically actuated amphibious origami millirobot that integrates capabilities of spinning-enabled multimodal locomotion, controlled delivery of liquid medicine, and cargo transportation with wireless operation. This millirobot takes full advantage of the geometrical features and folding/unfolding capability of Kresling origami, a triangulated hollow cylinder, to fulfill multifunction: its geometrical features are exploited for generating omnidirectional locomotion in various working environments, including on unstructured ground, in liquids, and at air-liquid interfaces through rolling, flipping, and spinning-induced propulsion; the folding/unfolding is utilized as a pumping mechanism for integrated multifunctionality such as controlled delivery of liquid medicine; furthermore, the spinning motion provides a sucking mechanism for targeted solid cargo transportation. This origami millirobot breaks the conventional way of utilizing origami folding only for shape reconfiguration and integrates multiple functions in one simple body. We anticipate the reported magnetic amphibious origami millirobots have the potential to serve as minimally invasive devices for biomedical diagnoses and treatments.