Abstract:In recent months, the monkeypox (mpox) virus -- previously endemic in a limited area of the world -- has started spreading in multiple countries until being declared a ``public health emergency of international concern'' by the World Health Organization. The alert was renewed in February 2023 due to a persisting sustained incidence of the virus in several countries and worries about possible new outbreaks. Low-income countries with inadequate infrastructures for vaccine and testing administration are particularly at risk. A symptom of mpox infection is the appearance of skin rashes and eruptions, which can drive people to seek medical advice. A technology that might help perform a preliminary screening based on the aspect of skin lesions is the use of Machine Learning for image classification. However, to make this technology suitable on a large scale, it should be usable directly on mobile devices of people, with a possible notification to a remote medical expert. In this work, we investigate the adoption of Deep Learning to detect mpox from skin lesion images. The proposal leverages Transfer Learning to cope with the scarce availability of mpox image datasets. As a first step, a homogenous, unpolluted, dataset is produced by manual selection and preprocessing of available image data. It will also be released publicly to researchers in the field. Then, a thorough comparison is conducted amongst several Convolutional Neural Networks, based on a 10-fold stratified cross-validation. The best models are then optimized through quantization for use on mobile devices; measures of classification quality, memory footprint, and processing times validate the feasibility of our proposal. Additionally, the use of eXplainable AI is investigated as a suitable instrument to both technically and clinically validate classification outcomes.
Abstract:Joint bleeding is a common condition for people with hemophilia and, if untreated, can result in hemophilic arthropathy. Ultrasound imaging has recently emerged as an effective tool to diagnose joint recess distension caused by joint bleeding. However, no computer-aided diagnosis tool exists to support the practitioner in the diagnosis process. This paper addresses the problem of automatically detecting the recess and assessing whether it is distended in knee ultrasound images collected in patients with hemophilia. After framing the problem, we propose two different approaches: the first one adopts a one-stage object detection algorithm, while the second one is a multi-task approach with a classification and a detection branch. The experimental evaluation, conducted with $483$ annotated images, shows that the solution based on object detection alone has a balanced accuracy score of $0.74$ with a mean IoU value of $0.66$, while the multi-task approach has a higher balanced accuracy value ($0.78$) at the cost of a slightly lower mean IoU value.