Second-order Anisotropic Gaussian Directional Derivative Filters for Blob Detection

Interest point detection methods have received increasing attention and are widely used in computer vision tasks such as image retrieval and 3D reconstruction. In this work, second-order anisotropic Gaussian directional derivative filters with multiple scales are used to smooth the input image and a novel blob detection method is proposed. Extensive experiments demonstrate the superiority of our proposed method over state-of-the-art benchmarks in terms of detection performance and robustness to affine transformations.

Recurrent convolutional neural networks for mandible segmentation from computed tomography

Recently, accurate mandible segmentation in CT scans based on deep learning methods has attracted much attention. However, there still exist two major challenges, namely, metal artifacts among mandibles and large variations in shape or size among individuals. To address these two challenges, we propose a recurrent segmentation convolutional neural network (RSegCNN) that embeds segmentation convolutional neural network (SegCNN) into the recurrent neural network (RNN) for robust and accurate segmentation of the mandible. Such a design of the system takes into account the similarity and continuity of the mandible shapes captured in adjacent image slices in CT scans. The RSegCNN infers the mandible information based on the recurrent structure with the embedded encoder-decoder segmentation (SegCNN) components. The recurrent structure guides the system to exploit relevant and important information from adjacent slices, while the SegCNN component focuses on the mandible shapes from a single CT slice. We conducted extensive experiments to evaluate the proposed RSegCNN on two head and neck CT datasets. The experimental results show that the RSegCNN is significantly better than the state-of-the-art models for accurate mandible segmentation.

Automatic Pulmonary Nodule Detection in CT Scans Using Convolutional Neural Networks Based on Maximum Intensity Projection

Accurate pulmonary nodule detection in computed tomography scans is a crucial step in lung cancer screening. Computer-aided detection (CAD) systems are not routinely used by radiologists for pulmonary nodules detection in clinical practice despite their potential benefits. Maximum intensity projection (MIP) images improve the detection of pulmonary nodules in radiological evaluation with computed tomography (CT) scans. In this work, we aim to explore the feasibility of utilizing MIP images to improve the effectiveness of automatic detection of lung nodules by convolutional neural networks (CNNs). We propose a CNN based approach that takes MIP images of different slab thicknesses (5 mm, 10 mm, 15 mm) and 1mm plain multiplanar reconstruction (MPR) images as input. Such an approach augments the 2-D CT slice images with more representative spatial information that helps in the discriminating nodules from vessels through their morphologies. We use the public available LUNA16 set collected from seven academic centers to train and test our approach. Our proposed method achieves a sensitivity of 91.13% with 1 false positive per scan and a sensitivity of 94.13% with 4 false positives per scan for lung nodule detection in this dataset. Using the thick MIP images helps the detection of small pulmonary nodules (3mm-10mm) and acquires fewer false positives. Experimental results show that applying MIP images can increase the sensitivity and lower the number of false positive, which demonstrates the effectiveness and significance of the proposed maximum intensity projection based CNN framework for automatic pulmonary nodule detection in CT scans. Index Terms: Computer-aided detection (CAD), convolutional neural networks (CNNs), computed tomography scans, maximum intensity projection (MIP), pulmonary nodule detection

3D segmentation of mandible from multisectional CT scans by convolutional neural networks

Segmentation of mandibles in CT scans during virtual surgical planning is crucial for 3D surgical planning in order to obtain a detailed surface representation of the patients bone. Automatic segmentation of mandibles in CT scans is a challenging task due to large variation in their shape and size between individuals. In order to address this challenge we propose a convolutional neural network approach for mandible segmentation in CT scans by considering the continuum of anatomical structures through different planes. The proposed convolutional neural network adopts the architecture of the U-Net and then combines the resulting 2D segmentations from three different planes into a 3D segmentation. We implement such a segmentation approach on 11 neck CT scans and then evaluate the performance. We achieve an average dice coefficient of $ 0.89 $ on two testing mandible segmentation. Experimental results show that our proposed approach for mandible segmentation in CT scans exhibits high accuracy.