Detecting and clustering swallow events in esophageal long-term high-resolution manometry

High-resolution manometry (HRM) is the gold standard in diagnosing esophageal motility disorders. As HRM is typically conducted under short-term laboratory settings, intermittently occurring disorders are likely to be missed. Therefore, long-term (up to 24h) HRM (LTHRM) is used to gain detailed insights into the swallowing behavior. However, analyzing the extensive data from LTHRM is challenging and time consuming as medical experts have to analyze the data manually, which is slow and prone to errors. To address this challenge, we propose a Deep Learning based swallowing detection method to accurately identify swallowing events and secondary non-deglutitive-induced esophageal motility disorders in LTHRM data. We then proceed with clustering the identified swallows into distinct classes, which are analyzed by highly experienced clinicians to validate the different swallowing patterns. We evaluate our computational pipeline on a total of 25 LTHRMs, which were meticulously annotated by medical experts. By detecting more than 94% of all relevant swallow events and providing all relevant clusters for a more reliable diagnostic process among experienced clinicians, we are able to demonstrate the effectiveness as well as positive clinical impact of our approach to make LTHRM feasible in clinical care.

Motion-Corrected Moving Average: Including Post-Hoc Temporal Information for Improved Video Segmentation

Real-time computational speed and a high degree of precision are requirements for computer-assisted interventions. Applying a segmentation network to a medical video processing task can introduce significant inter-frame prediction noise. Existing approaches can reduce inconsistencies by including temporal information but often impose requirements on the architecture or dataset. This paper proposes a method to include temporal information in any segmentation model and, thus, a technique to improve video segmentation performance without alterations during training or additional labeling. With Motion-Corrected Moving Average, we refine the exponential moving average between the current and previous predictions. Using optical flow to estimate the movement between consecutive frames, we can shift the prior term in the moving-average calculation to align with the geometry of the current frame. The optical flow calculation does not require the output of the model and can therefore be performed in parallel, leading to no significant runtime penalty for our approach. We evaluate our approach on two publicly available segmentation datasets and two proprietary endoscopic datasets and show improvements over a baseline approach.

MITI: SLAM Benchmark for Laparoscopic Surgery

We propose a new benchmark for evaluating stereoscopic visual-inertial computer vision algorithms (SLAM/ SfM/ 3D Reconstruction/ Visual-Inertial Odometry) for minimally invasive surgical (MIS) interventions in the abdomen. Our MITI Dataset available at [https://mediatum.ub.tum.de/1621941] provides all the necessary data by a complete recording of a handheld surgical intervention at Research Hospital Rechts der Isar of TUM. It contains multimodal sensor information from IMU, stereoscopic video, and infrared (IR) tracking as ground truth for evaluation. Furthermore, calibration for the stereoscope, accelerometer, magnetometer, the rigid transformations in the sensor setup, and time-offsets are available. We wisely chose a suitable intervention that contains very few cutting and tissue deformation and shows a full scan of the abdomen with a handheld camera such that it is ideal for testing SLAM algorithms. Intending to promote the progress of visual-inertial algorithms designed for MIS application, we hope that our clinical training dataset helps and enables researchers to enhance algorithms.

Constrained Visual-Inertial Localization With Application And Benchmark in Laparoscopic Surgery

We propose a novel method to tackle the visual-inertial localization problem for constrained camera movements. We use residuals from the different modalities to jointly optimize a global cost function. The residuals emerge from IMU measurements, stereoscopic feature points, and constraints on possible solutions in SE(3). In settings where dynamic disturbances are frequent, the residuals reduce the complexity of the problem and make localization feasible. We verify the advantages of our method in a suitable medical use case and produce a dataset capturing a minimally invasive surgery in the abdomen. Our novel clinical dataset MITI is comparable to state-of-the-art evaluation datasets, contains calibration and synchronization and is available at https://mediatum.ub.tum.de/1621941.