MCAT: Visual Query-Based Localization of Standard Anatomical Clips in Fetal Ultrasound Videos Using Multi-Tier Class-Aware Token Transformer

Accurate standard plane acquisition in fetal ultrasound (US) videos is crucial for fetal growth assessment, anomaly detection, and adherence to clinical guidelines. However, manually selecting standard frames is time-consuming and prone to intra- and inter-sonographer variability. Existing methods primarily rely on image-based approaches that capture standard frames and then classify the input frames across different anatomies. This ignores the dynamic nature of video acquisition and its interpretation. To address these challenges, we introduce Multi-Tier Class-Aware Token Transformer (MCAT), a visual query-based video clip localization (VQ-VCL) method, to assist sonographers by enabling them to capture a quick US sweep. By then providing a visual query of the anatomy they wish to analyze, MCAT returns the video clip containing the standard frames for that anatomy, facilitating thorough screening for potential anomalies. We evaluate MCAT on two ultrasound video datasets and a natural image VQ-VCL dataset based on Ego4D. Our model outperforms state-of-the-art methods by 10% and 13% mIoU on the ultrasound datasets and by 5.35% mIoU on the Ego4D dataset, using 96% fewer tokens. MCAT's efficiency and accuracy have significant potential implications for public health, especially in low- and middle-income countries (LMICs), where it may enhance prenatal care by streamlining standard plane acquisition, simplifying US-based screening, diagnosis and allowing sonographers to examine more patients.

Self-supervised Normality Learning and Divergence Vector-guided Model Merging for Zero-shot Congenital Heart Disease Detection in Fetal Ultrasound Videos

Congenital Heart Disease (CHD) is one of the leading causes of fetal mortality, yet the scarcity of labeled CHD data and strict privacy regulations surrounding fetal ultrasound (US) imaging present significant challenges for the development of deep learning-based models for CHD detection. Centralised collection of large real-world datasets for rare conditions, such as CHD, from large populations requires significant co-ordination and resource. In addition, data governance rules increasingly prevent data sharing between sites. To address these challenges, we introduce, for the first time, a novel privacy-preserving, zero-shot CHD detection framework that formulates CHD detection as a normality modeling problem integrated with model merging. In our framework dubbed Sparse Tube Ultrasound Distillation (STUD), each hospital site first trains a sparse video tube-based self-supervised video anomaly detection (VAD) model on normal fetal heart US clips with self-distillation loss. This enables site-specific models to independently learn the distribution of healthy cases. To aggregate knowledge across the decentralized models while maintaining privacy, we propose a Divergence Vector-Guided Model Merging approach, DivMerge, that combines site-specific models into a single VAD model without data exchange. Our approach preserves domain-agnostic rich spatio-temporal representations, ensuring generalization to unseen CHD cases. We evaluated our approach on real-world fetal US data collected from 5 hospital sites. Our merged model outperformed site-specific models by 23.77% and 30.13% in accuracy and F1-score respectively on external test sets.

A Dual Adversarial Calibration Framework for Automatic Fetal Brain Biometry

This paper presents a novel approach to automatic fetal brain biometry motivated by needs in low- and medium- income countries. Specifically, we leverage high-end (HE) ultrasound images to build a biometry solution for low-cost (LC) point-of-care ultrasound images. We propose a novel unsupervised domain adaptation approach to train deep models to be invariant to significant image distribution shift between the image types. Our proposed method, which employs a Dual Adversarial Calibration (DAC) framework, consists of adversarial pathways which enforce model invariance to; i) adversarial perturbations in the feature space derived from LC images, and ii) appearance domain discrepancy. Our Dual Adversarial Calibration method estimates transcerebellar diameter and head circumference on images from low-cost ultrasound devices with a mean absolute error (MAE) of 2.43mm and 1.65mm, compared with 7.28 mm and 5.65 mm respectively for SOTA.