The nature of diversity in real-world environments necessitates neural network models to expand from closed category settings to accommodate novel emerging categories. In this paper, we study the open-vocabulary object detection (OVD), which facilitates the detection of novel object classes under the supervision of only base annotations and open-vocabulary knowledge. However, we find that the inadequacy of neighboring relationships between regions during the alignment process inevitably constrains the performance on recent distillation-based OVD strategies. To this end, we propose Neighboring Region Attention Alignment (NRAA), which performs alignment within the attention mechanism of a set of neighboring regions to boost the open-vocabulary inference. Specifically, for a given proposal region, we randomly explore the neighboring boxes and conduct our proposed neighboring region attention (NRA) mechanism to extract relationship information. Then, this interaction information is seamlessly provided into the distillation procedure to assist the alignment between the detector and the pre-trained vision-language models (VLMs). Extensive experiments validate that our proposed model exhibits superior performance on open-vocabulary benchmarks.