Large language models (LLMs) increasingly rely on preference alignment methods to steer outputs toward human values, yet these methods are often constrained by the scarcity of high-quality human-annotated data. To tackle this, recent approaches have turned to synthetic data generated by LLMs as a scalable alternative. However, synthetic data can introduce distribution shifts, compromising the nuanced human preferences that are essential for desirable outputs. In this paper, we propose a novel distribution-aware optimization framework that improves preference alignment in the presence of such shifts. Our approach first estimates the likelihood ratios between the target and training distributions leveraging a learned classifier, then it minimizes the worst-case loss over data regions that reflect the target human-preferred distribution. By explicitly prioritizing the target distribution during optimization, our method mitigates the adverse effects of distributional variation and enhances the generation of responses that faithfully reflect human values.