This paper investigates the performance tradeoff for a multi-antenna integrated sensing and communication (ISAC) system with simultaneous information multicasting and multi-target sensing, in which a multi-antenna base station (BS) sends the common information messages to a set of single-antenna communication users (CUs) and estimates the parameters of multiple sensing targets based on the echo signals concurrently. We consider two target sensing scenarios without and with prior target knowledge at the BS, in which the BS is interested in estimating the complete multi-target response matrix and the target reflection coefficients/angles, respectively. First, we consider the capacity-achieving transmission and characterize the fundamental tradeoff between the achievable rate and the multi-target estimation Cram\'er-Rao bound (CRB) accordingly.