Recommender Systems (RSs) provide personalized recommendation service based on user interest, which are widely used in various platforms. However, there are lots of users with sparse interest due to lacking consumption behaviors, which leads to poor recommendation results for them. This problem is widespread in large-scale RSs and is particularly difficult to address. To solve this problem, we propose a novel solution named User Interest Enhancement (UIE) which enhances user interest including user profile and user history behavior sequences using the enhancement vectors and personalized enhancement vector generated based on stream clustering and memory networks from different perspectives. UIE not only remarkably improves model performance on the users with sparse interest but also significantly enhance model performance on other users. UIE is an end-to-end solution which is easy to be implemented based on ranking model. Moreover, we expand our solution and apply similar methods to long-tail items, which also achieves excellent improvement. Furthermore, we conduct extensive offline and online experiments in a large-scale industrial RS. The results demonstrate that our model outperforms other models remarkably, especially for the users with sparse interest. Until now, UIE has been fully deployed in multiple large-scale RSs and achieved remarkable improvements.