A General Close-loop Predictive Coding Framework for Auditory Working Memory

Auditory working memory is essential for various daily activities, such as language acquisition, conversation. It involves the temporary storage and manipulation of information that is no longer present in the environment. While extensively studied in neuroscience and cognitive science, research on its modeling within neural networks remains limited. To address this gap, we propose a general framework based on a close-loop predictive coding paradigm to perform short auditory signal memory tasks. The framework is evaluated on two widely used benchmark datasets for environmental sound and speech, demonstrating high semantic similarity across both datasets.

A Reservoir-based Model for Human-like Perception of Complex Rhythm Pattern

Rhythm is a fundamental aspect of human behaviour, present from infancy and deeply embedded in cultural practices. Rhythm anticipation is a spontaneous cognitive process that typically occurs before the onset of actual beats. While most research in both neuroscience and artificial intelligence has focused on metronome-based rhythm tasks, studies investigating the perception of complex musical rhythm patterns remain limited. To address this gap, we propose a hierarchical oscillator-based model to better understand the perception of complex musical rhythms in biological systems. The model consists of two types of coupled neurons that generate oscillations, with different layers tuned to respond to distinct perception levels. We evaluate the model using several representative rhythm patterns spanning the upper, middle, and lower bounds of human musical perception. Our findings demonstrate that, while maintaining a high degree of synchronization accuracy, the model exhibits human-like rhythmic behaviours. Additionally, the beta band neuronal activity in the model mirrors patterns observed in the human brain, further validating the biological plausibility of the approach.

A novel Reservoir Architecture for Periodic Time Series Prediction

This paper introduces a novel approach to predicting periodic time series using reservoir computing. The model is tailored to deliver precise forecasts of rhythms, a crucial aspect for tasks such as generating musical rhythm. Leveraging reservoir computing, our proposed method is ultimately oriented towards predicting human perception of rhythm. Our network accurately predicts rhythmic signals within the human frequency perception range. The model architecture incorporates primary and intermediate neurons tasked with capturing and transmitting rhythmic information. Two parameter matrices, denoted as c and k, regulate the reservoir's overall dynamics. We propose a loss function to adapt c post-training and introduce a dynamic selection (DS) mechanism that adjusts $k$ to focus on areas with outstanding contributions. Experimental results on a diverse test set showcase accurate predictions, further improved through real-time tuning of the reservoir via c and k. Comparative assessments highlight its superior performance compared to conventional models.

AF2-Mutation: Adversarial Sequence Mutations against AlphaFold2 on Protein Tertiary Structure Prediction

Deep learning-based approaches, such as AlphaFold2 (AF2), have significantly advanced protein tertiary structure prediction, achieving results comparable to real biological experimental methods. While AF2 has shown limitations in predicting the effects of mutations, its robustness against sequence mutations remains to be determined. Starting with the wild-type (WT) sequence, we investigate adversarial sequences generated via an evolutionary approach, which AF2 predicts to be substantially different from WT. Our experiments on CASP14 reveal that by modifying merely three residues in the protein sequence using a combination of replacement, deletion, and insertion strategies, the alteration in AF2's predictions, as measured by the Local Distance Difference Test (lDDT), reaches 46.61. Moreover, when applied to a specific protein, SPNS2, our proposed algorithm successfully identifies biologically meaningful residues critical to protein structure determination and potentially indicates alternative conformations, thus significantly expediting the experimental process.

Cross-Domain Few-Shot Relation Extraction via Representation Learning and Domain Adaptation

Cross-domain few-shot relation extraction poses a great challenge for the existing few-shot learning methods and domain adaptation methods when the source domain and target domain have large discrepancies. This paper proposes a method by combining the idea of few-shot learning and domain adaptation to deal with this problem. In the proposed method, an encoder, learned by optimizing a representation loss and an adversarial loss, is used to extract the relation of sentences in the source and target domain. The representation loss, including a cross-entropy loss and a contrastive loss, makes the encoder extract the relation of the source domain and keep the geometric structure of the classes in the source domain. And the adversarial loss is used to merge the source domain and target domain. The experimental results on the benchmark FewRel dataset demonstrate that the proposed method can outperform some state-of-the-art methods.