Efficient MedSAMs: Segment Anything in Medical Images on Laptop

Promptable segmentation foundation models have emerged as a transformative approach to addressing the diverse needs in medical images, but most existing models require expensive computing, posing a big barrier to their adoption in clinical practice. In this work, we organized the first international competition dedicated to promptable medical image segmentation, featuring a large-scale dataset spanning nine common imaging modalities from over 20 different institutions. The top teams developed lightweight segmentation foundation models and implemented an efficient inference pipeline that substantially reduced computational requirements while maintaining state-of-the-art segmentation accuracy. Moreover, the post-challenge phase advanced the algorithms through the design of performance booster and reproducibility tasks, resulting in improved algorithms and validated reproducibility of the winning solution. Furthermore, the best-performing algorithms have been incorporated into the open-source software with a user-friendly interface to facilitate clinical adoption. The data and code are publicly available to foster the further development of medical image segmentation foundation models and pave the way for impactful real-world applications.

XctDiff: Reconstruction of CT Images with Consistent Anatomical Structures from a Single Radiographic Projection Image

In this paper, we present XctDiff, an algorithm framework for reconstructing CT from a single radiograph, which decomposes the reconstruction process into two easily controllable tasks: feature extraction and CT reconstruction. Specifically, we first design a progressive feature extraction strategy that is able to extract robust 3D priors from radiographs. Then, we use the extracted prior information to guide the CT reconstruction in the latent space. Moreover, we design a homogeneous spatial codebook to improve the reconstruction quality further. The experimental results show that our proposed method achieves state-of-the-art reconstruction performance and overcomes the blurring issue. We also apply XctDiff on self-supervised pre-training task. The effectiveness indicates that it has promising additional applications in medical image analysis. The code is available at:https://github.com/qingze-bai/XctDiff