Score-based Generative Priors Guided Model-driven Network for MRI Reconstruction

Score matching with Langevin dynamics (SMLD) method has been successfully applied to accelerated MRI. However, the hyperparameters in the sampling process require subtle tuning, otherwise the results can be severely corrupted by hallucination artifacts, particularly with out-of-distribution test data. In this study, we propose a novel workflow in which SMLD results are regarded as additional priors to guide model-driven network training. First, we adopted a pretrained score network to obtain samples as preliminary guidance images (PGI) without the need for network retraining, parameter tuning and in-distribution test data. Although PGIs are corrupted by hallucination artifacts, we believe that they can provide extra information through effective denoising steps to facilitate reconstruction. Therefore, we designed a denoising module (DM) in the second step to improve the quality of PGIs. The features are extracted from the components of Langevin dynamics and the same score network with fine-tuning; hence, we can directly learn the artifact patterns. Third, we designed a model-driven network whose training is guided by denoised PGIs (DGIs). DGIs are densely connected with intermediate reconstructions in each cascade to enrich the features and are periodically updated to provide more accurate guidance. Our experiments on different sequences revealed that despite the low average quality of PGIs, the proposed workflow can effectively extract valuable information to guide the network training, even with severely reduced training data and sampling steps. Our method outperforms other cutting-edge techniques by effectively mitigating hallucination artifacts, yielding robust and high-quality reconstruction results.

A Collaborative Model-driven Network for MRI Reconstruction

Magnetic resonance imaging (MRI) is a vital medical imaging modality, but its development has been limited by prolonged scanning time. Deep learning (DL)-based methods, which build neural networks to reconstruct MR images from undersampled raw data, can reliably address this problem. Among these methods, model-driven DL methods incorporate different prior knowledge into deep networks, thereby narrowing the solution space and achieving better results. However, the complementarity among different prior knowledge has not been thoroughly explored. Most of the existing model-driven networks simply stack unrolled cascades to mimic iterative solution steps, which are inefficient and their performances are suboptimal. To optimize the conventional network structure, we propose a collaborative model-driven network. In the network, each unrolled cascade comprised three parts: model-driven subnetworks, attention modules, and correction modules. The attention modules can learn to enhance the areas of expertise for each subnetwork, and the correction modules can compensate for new errors caused by the attention modules. The optimized intermediate results are fed into the next cascade for better convergence. Experimental results on multiple sequences showed significant improvements in the final results without additional computational complexity. Moreover, the proposed model-driven network design strategy can be easily applied to other model-driven methods to improve their performances.