EAUWSeg: Eliminating annotation uncertainty in weakly-supervised medical image segmentation

Weakly-supervised medical image segmentation is gaining traction as it requires only rough annotations rather than accurate pixel-to-pixel labels, thereby reducing the workload for specialists. Although some progress has been made, there is still a considerable performance gap between the label-efficient methods and fully-supervised one, which can be attributed to the uncertainty nature of these weak labels. To address this issue, we propose a novel weak annotation method coupled with its learning framework EAUWSeg to eliminate the annotation uncertainty. Specifically, we first propose the Bounded Polygon Annotation (BPAnno) by simply labeling two polygons for a lesion. Then, the tailored learning mechanism that explicitly treat bounded polygons as two separated annotations is proposed to learn invariant feature by providing adversarial supervision signal for model training. Subsequently, a confidence-auxiliary consistency learner incorporates with a classification-guided confidence generator is designed to provide reliable supervision signal for pixels in uncertain region by leveraging the feature presentation consistency across pixels within the same category as well as class-specific information encapsulated in bounded polygons annotation. Experimental results demonstrate that EAUWSeg outperforms existing weakly-supervised segmentation methods. Furthermore, compared to fully-supervised counterparts, the proposed method not only delivers superior performance but also costs much less annotation workload. This underscores the superiority and effectiveness of our approach.

Adaptive Hardness-driven Augmentation and Alignment Strategies for Multi-Source Domain Adaptations

Multi-source Domain Adaptation (MDA) aims to transfer knowledge from multiple labeled source domains to an unlabeled target domain. Nevertheless, traditional methods primarily focus on achieving inter-domain alignment through sample-level constraints, such as Maximum Mean Discrepancy (MMD), neglecting three pivotal aspects: 1) the potential of data augmentation, 2) the significance of intra-domain alignment, and 3) the design of cluster-level constraints. In this paper, we introduce a novel hardness-driven strategy for MDA tasks, named "A3MDA" , which collectively considers these three aspects through Adaptive hardness quantification and utilization in both data Augmentation and domain Alignment.To achieve this, "A3MDA" progressively proposes three Adaptive Hardness Measurements (AHM), i.e., Basic, Smooth, and Comparative AHMs, each incorporating distinct mechanisms for diverse scenarios. Specifically, Basic AHM aims to gauge the instantaneous hardness for each source/target sample. Then, hardness values measured by Smooth AHM will adaptively adjust the intensity level of strong data augmentation to maintain compatibility with the model's generalization capacity.In contrast, Comparative AHM is designed to facilitate cluster-level constraints. By leveraging hardness values as sample-specific weights, the traditional MMD is enhanced into a weighted-clustered variant, strengthening the robustness and precision of inter-domain alignment. As for the often-neglected intra-domain alignment, we adaptively construct a pseudo-contrastive matrix by selecting harder samples based on the hardness rankings, enhancing the quality of pseudo-labels, and shaping a well-clustered target feature space. Experiments on multiple MDA benchmarks show that " A3MDA " outperforms other methods.

Judge Like a Real Doctor: Dual Teacher Sample Consistency Framework for Semi-supervised Medical Image Classification

Semi-supervised learning (SSL) is a popular solution to alleviate the high annotation cost in medical image classification. As a main branch of SSL, consistency regularization engages in imposing consensus between the predictions of a single sample from different views, termed as Absolute Location consistency (AL-c). However, only AL-c may be insufficient. Just like when diagnosing a case in practice, besides the case itself, the doctor usually refers to certain related trustworthy cases to make more reliable decisions.Therefore, we argue that solely relying on AL-c may ignore the relative differences across samples, which we interpret as relative locations, and only exploit limited information from one perspective. To address this issue, we propose a Sample Consistency Mean Teacher (SCMT) which not only incorporates AL c but also additionally enforces consistency between the samples' relative similarities to its related samples, called Relative Location consistency (RL c). AL c and RL c conduct consistency regularization from two different perspectives, jointly extracting more diverse semantic information for classification. On the other hand, due to the highly similar structures in medical images, the sample distribution could be overly dense in feature space, making their relative locations susceptible to noise. To tackle this problem, we further develop a Sample Scatter Mean Teacher (SSMT) by utilizing contrastive learning to sparsify the sample distribution and obtain robust and effective relative locations. Extensive experiments on different datasets demonstrate the superiority of our method.

Visual Recognition by Counting Instances: A Multi-Instance Cardinality Potential Kernel

Many visual recognition problems can be approached by counting instances. To determine whether an event is present in a long internet video, one could count how many frames seem to contain the activity. Classifying the activity of a group of people can be done by counting the actions of individual people. Encoding these cardinality relationships can reduce sensitivity to clutter, in the form of irrelevant frames or individuals not involved in a group activity. Learned parameters can encode how many instances tend to occur in a class of interest. To this end, this paper develops a powerful and flexible framework to infer any cardinality relation between latent labels in a multi-instance model. Hard or soft cardinality relations can be encoded to tackle diverse levels of ambiguity. Experiments on tasks such as human activity recognition, video event detection, and video summarization demonstrate the effectiveness of using cardinality relations for improving recognition results.