Abstract:The proceedings of Workshop Scientific HPC in the pre-Exascale era (SHPC), held in Pisa, Italy, September 18, 2024, are part of 3rd Italian Conference on Big Data and Data Science (ITADATA2024) proceedings (arXiv: 2503.14937). The main objective of SHPC workshop was to discuss how the current most critical questions in HPC emerge in astrophysics, cosmology, and other scientific contexts and experiments. In particular, SHPC workshop focused on: $\bullet$ Scientific (mainly in astrophysical and medical fields) applications toward (pre-)Exascale computing $\bullet$ Performance portability $\bullet$ Green computing $\bullet$ Machine learning $\bullet$ Big Data management $\bullet$ Programming on heterogeneous architectures $\bullet$ Programming on accelerators $\bullet$ I/O techniques