Deep End-to-End Survival Analysis with Temporal Consistency

In this study, we present a novel Survival Analysis algorithm designed to efficiently handle large-scale longitudinal data. Our approach draws inspiration from Reinforcement Learning principles, particularly the Deep Q-Network paradigm, extending Temporal Learning concepts to Survival Regression. A central idea in our method is temporal consistency, a hypothesis that past and future outcomes in the data evolve smoothly over time. Our framework uniquely incorporates temporal consistency into large datasets by providing a stable training signal that captures long-term temporal relationships and ensures reliable updates. Additionally, the method supports arbitrarily complex architectures, enabling the modeling of intricate temporal dependencies, and allows for end-to-end training. Through numerous experiments we provide empirical evidence demonstrating our framework's ability to exploit temporal consistency across datasets of varying sizes. Moreover, our algorithm outperforms benchmarks on datasets with long sequences, demonstrating its ability to capture long-term patterns. Finally, ablation studies show how our method enhances training stability.

Learning Generative Models with Goal-conditioned Reinforcement Learning

We present a novel, alternative framework for learning generative models with goal-conditioned reinforcement learning. We define two agents, a goal conditioned agent (GC-agent) and a supervised agent (S-agent). Given a user-input initial state, the GC-agent learns to reconstruct the training set. In this context, elements in the training set are the goals. During training, the S-agent learns to imitate the GC-agent while remaining agnostic of the goals. At inference we generate new samples with the S-agent. Following a similar route as in variational auto-encoders, we derive an upper bound on the negative log-likelihood that consists of a reconstruction term and a divergence between the GC-agent policy and the (goal-agnostic) S-agent policy. We empirically demonstrate that our method is able to generate diverse and high quality samples in the task of image synthesis.