Abstract:In recent years, the rapid aging of the global population has led to an increase in cognitive disorders, such as Alzheimer's disease, presenting significant public health challenges. Although no effective treatments currently exist to reverse Alzheimer's, prevention and early intervention, including cognitive training, are critical. This report explores the potential of AI chatbots in enhancing personalized cognitive training. We introduce ReMe, a web-based framework designed to create AI chatbots that facilitate cognitive training research, specifically targeting episodic memory tasks derived from personal life logs. By leveraging large language models, ReMe provides enhanced user-friendly, interactive, and personalized training experiences. Case studies demonstrate ReMe's effectiveness in engaging users through life recall and open-ended language puzzles, highlighting its potential to improve cognitive training design. Despite promising results, further research is needed to validate training effectiveness through large-scale studies that include cognitive ability evaluations. Overall, ReMe offers a promising approach to personalized cognitive training, utilizing AI capabilities to meet the growing demand for non-pharmacological interventions in cognitive health, with future research aiming to expand its applications and efficacy.