This paper addresses the generation of referring expressions that not only refer to objects correctly but also ease human comprehension. As the composition of an image becomes more complicated and a target becomes relatively less salient, identifying referred objects comes more difficult. However, the existing studies regarded all sentences that refer to objects correctly as equally good, ignoring whether they are easily understood by humans. If the target is not salient, humans utilize relationships with the salient contexts around it to help listeners to comprehend it better. To derive these information from human annotations, our model is designed to extract information from the inside and outside of the target. Moreover, we regard that sentences that are easily understood are those that are comprehended correctly and quickly by humans. We optimized it by using the time required to locate the referred objects by humans and their accuracies. To evaluate our system, we created a new referring expression dataset whose images were acquired from Grand Theft Auto V (GTA V), limiting targets to persons. Our proposed method outperformed previous methods both on machine evaluation and on crowd-sourced human evaluation. The source code and dataset will be available soon.