Recently, Meta AI Research approaches a general, promptable Segment Anything Model (SAM) pre-trained on an unprecedentedly large segmentation dataset (SA-1B). Without a doubt, the emergence of SAM will yield significant benefits for a wide array of practical image segmentation applications. In this study, we conduct a series of intriguing investigations into the performance of SAM across various applications, particularly in the fields of natural images, agriculture, manufacturing, remote sensing, and healthcare. We analyze and discuss the benefits and limitations of SAM and provide an outlook on future development of segmentation tasks. Note that our work does not intend to propose new algorithms or theories, but rather provide a comprehensive view of SAM in practice. This work is expected to provide insights that facilitate future research activities toward generic segmentation.