3D visual grounding aims to automatically locate the 3D region of the specified object given the corresponding textual description. Existing works fail to distinguish similar objects especially when multiple referred objects are involved in the description. Experiments show that direct matching of language and visual modal has limited capacity to comprehend complex referential relationships in utterances. It is mainly due to the interference caused by redundant visual information in cross-modal alignment. To strengthen relation-orientated mapping between different modalities, we propose SeCG, a semantic-enhanced relational learning model based on a graph network with our designed memory graph attention layer. Our method replaces original language-independent encoding with cross-modal encoding in visual analysis. More text-related feature expressions are obtained through the guidance of global semantics and implicit relationships. Experimental results on ReferIt3D and ScanRefer benchmarks show that the proposed method outperforms the existing state-of-the-art methods, particularly improving the localization performance for the multi-relation challenges.