Remote sensing plays a crucial role in monitoring Earth's ecosystems, yet satellite-derived data often suffer from limited spatial resolution, restricting their applicability in atmospheric modeling and climate research. In this work, we propose a deep learning-based Super-Resolution (SR) framework that leverages land cover information to enhance the spatial accuracy of Biogenic Volatile Organic Compounds (BVOCs) emissions, with a particular focus on isoprene. Our approach integrates land cover priors as emission drivers, capturing spatial patterns more effectively than traditional methods. We evaluate the model's performance across various climate conditions and analyze statistical correlations between isoprene emissions and key environmental information such as cropland and tree cover data. Additionally, we assess the generalization capabilities of our SR model by applying it to unseen climate zones and geographical regions. Experimental results demonstrate that incorporating land cover data significantly improves emission SR accuracy, particularly in heterogeneous landscapes. This study contributes to atmospheric chemistry and climate modeling by providing a cost-effective, data-driven approach to refining BVOC emission maps. The proposed method enhances the usability of satellite-based emissions data, supporting applications in air quality forecasting, climate impact assessments, and environmental studies.