Generating reliable pseudo masks from image-level labels is challenging in the weakly supervised semantic segmentation (WSSS) task due to the lack of spatial information. Prevalent class activation map (CAM)-based solutions are challenged to discriminate the foreground (FG) objects from the suspicious background (BG) pixels (a.k.a. co-occurring) and learn the integral object regions. This paper proposes a simple fine-grained background representation (FBR) method to discover and represent diverse BG semantics and address the co-occurring problems. We abandon using the class prototype or pixel-level features for BG representation. Instead, we develop a novel primitive, negative region of interest (NROI), to capture the fine-grained BG semantic information and conduct the pixel-to-NROI contrast to distinguish the confusing BG pixels. We also present an active sampling strategy to mine the FG negatives on-the-fly, enabling efficient pixel-to-pixel intra-foreground contrastive learning to activate the entire object region. Thanks to the simplicity of design and convenience in use, our proposed method can be seamlessly plugged into various models, yielding new state-of-the-art results under various WSSS settings across benchmarks. Leveraging solely image-level (I) labels as supervision, our method achieves 73.2 mIoU and 45.6 mIoU segmentation results on Pascal Voc and MS COCO test sets, respectively. Furthermore, by incorporating saliency maps as an additional supervision signal (I+S), we attain 74.9 mIoU on Pascal Voc test set. Concurrently, our FBR approach demonstrates meaningful performance gains in weakly-supervised instance segmentation (WSIS) tasks, showcasing its robustness and strong generalization capabilities across diverse domains.