Cross-attention has become a fundamental module nowadays in many important artificial intelligence applications, e.g., retrieval-augmented generation (RAG), system prompt, guided stable diffusion, and many so on. Ensuring cross-attention privacy is crucial and urgently needed because its key and value matrices may contain sensitive information about companies and their users, many of which profit solely from their system prompts or RAG data. In this work, we design a novel differential privacy (DP) data structure to address the privacy security of cross-attention with a theoretical guarantee. In detail, let $n$ be the input token length of system prompt/RAG data, $d$ be the feature dimension, $0 < \alpha \le 1$ be the relative error parameter, $R$ be the maximum value of the query and key matrices, $R_w$ be the maximum value of the value matrix, and $r,s,\epsilon_s$ be parameters of polynomial kernel methods. Then, our data structure requires $\widetilde{O}(ndr^2)$ memory consumption with $\widetilde{O}(nr^2)$ initialization time complexity and $\widetilde{O}(\alpha^{-1} r^2)$ query time complexity for a single token query. In addition, our data structure can guarantee that the user query is $(\epsilon, \delta)$-DP with $\widetilde{O}(n^{-1} \epsilon^{-1} \alpha^{-1/2} R^{2s} R_w r^2)$ additive error and $n^{-1} (\alpha + \epsilon_s)$ relative error between our output and the true answer. Furthermore, our result is robust to adaptive queries in which users can intentionally attack the cross-attention system. To our knowledge, this is the first work to provide DP for cross-attention. We believe it can inspire more privacy algorithm design in large generative models (LGMs).