In the digital age, the proliferation of deep learning models has led to significant concerns about the generation of Not Safe for Work (NSFW) content. Existing defense methods primarily involve model fine-tuning and post-hoc content moderation. However, these approaches often lack scalability in eliminating harmful content, degrade the quality of benign image generation, or incur high inference costs. To tackle these challenges, we propose an innovative framework called \textbf{Buster}, which injects backdoor attacks into the text encoder to prevent NSFW content generation. Specifically, Buster leverages deep semantic information rather than explicit prompts as triggers, redirecting NSFW prompts towards targeted benign prompts. This approach demonstrates exceptional resilience and scalability in mitigating NSFW content. Remarkably, Buster fine-tunes the text encoder of Text-to-Image models within just five minutes, showcasing high efficiency. Our extensive experiments reveal that Buster outperforms all other baselines, achieving superior NSFW content removal rate while preserving the quality of harmless images.