The segment-anything model (SAM), was introduced as a fundamental model for segmenting images. It was trained using over 1 billion masks from 11 million natural images. The model can perform zero-shot segmentation of images by using various prompts such as masks, boxes, and points. In this report, we explored (1) the accuracy of SAM on 12 public medical image segmentation datasets which cover various organs (brain, breast, chest, lung, skin, liver, bowel, pancreas, and prostate), image modalities (2D X-ray, histology, endoscropy, and 3D MRI and CT), and health conditions (normal, lesioned). (2) if the computer vision foundational segmentation model SAM can provide promising research directions for medical image segmentation. We found that SAM without re-training on medical images does not perform as accurately as U-Net or other deep learning models trained on medical images.