Humans' ability to smoothly switch between locomotion and manipulation is a remarkable feature of sensorimotor coordination. Leaning and replication of such human-like strategies can lead to the development of more sophisticated robots capable of performing complex whole-body tasks in real-world environments. To this end, this paper proposes a combined learning and optimization framework for transferring human's loco-manipulation soft-switching skills to mobile manipulators. The methodology departs from data collection of human demonstrations for a locomotion-integrated manipulation task through a vision system. Next, the wrist and pelvis motions are mapped to mobile manipulators' End-Effector (EE) and mobile base. A kernelized movement primitive algorithm learns the wrist and pelvis trajectories and generalizes to new desired points according to task requirements. Next, the reference trajectories are sent to a hierarchical quadratic programming controller, where the EE and the mobile base reference trajectories are provided as the first and second priority tasks, generating the feasible and optimal joint level commands. A locomotion-integrated pick-and-place task is executed to validate the proposed approach. After a human demonstrates the task, a mobile manipulator executes the task with the same and new settings, grasping a bottle at non-zero velocity. The results showed that the proposed approach successfully transfers the human loco-manipulation skills to mobile manipulators, even with different geometry.