Explainable Deep Learning Algorithm for Distinguishing Incomplete Kawasaki Disease by Coronary Artery Lesions on Echocardiographic Imaging

Background and Objective: Incomplete Kawasaki disease (KD) has often been misdiagnosed due to a lack of the clinical manifestations of classic KD. However, it is associated with a markedly higher prevalence of coronary artery lesions. Identifying coronary artery lesions by echocardiography is important for the timely diagnosis of and favorable outcomes in KD. Moreover, similar to KD, coronavirus disease 2019, currently causing a worldwide pandemic, also manifests with fever; therefore, it is crucial at this moment that KD should be distinguished clearly among the febrile diseases in children. In this study, we aimed to validate a deep learning algorithm for classification of KD and other acute febrile diseases. Methods: We obtained coronary artery images by echocardiography of children (n = 88 for KD; n = 65 for pneumonia). We trained six deep learning networks (VGG19, Xception, ResNet50, ResNext50, SE-ResNet50, and SE-ResNext50) using the collected data. Results: SE-ResNext50 showed the best performance in terms of accuracy, specificity, and precision in the classification. SE-ResNext50 offered a precision of 76.35%, a sensitivity of 82.64%, and a specificity of 58.12%. Conclusions: The results of our study suggested that deep learning algorithms have similar performance to an experienced cardiologist in detecting coronary artery lesions to facilitate the diagnosis of KD.

Cyclops: Open Platform for Scale Truck Platooning

Cyclops, introduced in this paper, is an open research platform for everyone that wants to validate novel ideas and approaches in the area of self-driving heavy-duty vehicle platooning. The platform consists of multiple 1/14 scale semi-trailer trucks, a scale proving ground, and associated computing, communication and control modules that enable self-driving on the proving ground. A perception system for each vehicle is composed of a lidar-based object tracking system and a lane detection/control system. The former is to maintain the gap to the leading vehicle and the latter is to maintain the vehicle within the lane by steering control. The lane detection system is optimized for truck platooning where the field of view of the front-facing camera is severely limited due to a small gap to the leading vehicle. This platform is particularly amenable to validate mitigation strategies for safety-critical situations. Indeed, a simplex structure is adopted in the embedded module for testing various fail safe operations. We illustrate a scenario where camera sensor fails in the perception system but the vehicle operates at a reduced capacity to a graceful stop. Details of the Cyclops including 3D CAD designs and algorithm source codes are released for those who want to build similar testbeds.