Multi-Source EEG Emotion Recognition via Dynamic Contrastive Domain Adaptation

Electroencephalography (EEG) provides reliable indications of human cognition and mental states. Accurate emotion recognition from EEG remains challenging due to signal variations among individuals and across measurement sessions. To address these challenges, we introduce a multi-source dynamic contrastive domain adaptation method (MS-DCDA), which models coarse-grained inter-domain and fine-grained intra-class adaptations through a multi-branch contrastive neural network and contrastive sub-domain discrepancy learning. Our model leverages domain knowledge from each individual source and a complementary source ensemble and uses dynamically weighted learning to achieve an optimal tradeoff between domain transferability and discriminability. The proposed MS-DCDA model was evaluated using the SEED and SEED-IV datasets, achieving respectively the highest mean accuracies of $90.84\%$ and $78.49\%$ in cross-subject experiments as well as $95.82\%$ and $82.25\%$ in cross-session experiments. Our model outperforms several alternative domain adaptation methods in recognition accuracy, inter-class margin, and intra-class compactness. Our study also suggests greater emotional sensitivity in the frontal and parietal brain lobes, providing insights for mental health interventions, personalized medicine, and development of preventive strategies.

Kernel Cox partially linear regression: building predictive models for cancer patients' survival

Wide heterogeneity exists in cancer patients' survival, ranging from a few months to several decades. To accurately predict clinical outcomes, it is vital to build an accurate predictive model that relates patients' molecular profiles with patients' survival. With complex relationships between survival and high-dimensional molecular predictors, it is challenging to conduct non-parametric modeling and irrelevant predictors removing simultaneously. In this paper, we build a kernel Cox proportional hazards semi-parametric model and propose a novel regularized garrotized kernel machine (RegGKM) method to fit the model. We use the kernel machine method to describe the complex relationship between survival and predictors, while automatically removing irrelevant parametric and non-parametric predictors through a LASSO penalty. An efficient high-dimensional algorithm is developed for the proposed method. Comparison with other competing methods in simulation shows that the proposed method always has better predictive accuracy. We apply this method to analyze a multiple myeloma dataset and predict patients' death burden based on their gene expressions. Our results can help classify patients into groups with different death risks, facilitating treatment for better clinical outcomes.