Modelling Patient Trajectories Using Multimodal Information

Electronic Health Records (EHRs) aggregate diverse information at the patient level, holding a trajectory representative of the evolution of the patient health status throughout time. Although this information provides context and can be leveraged by physicians to monitor patient health and make more accurate prognoses/diagnoses, patient records can contain information from very long time spans, which combined with the rapid generation rate of medical data makes clinical decision making more complex. Patient trajectory modelling can assist by exploring existing information in a scalable manner, and can contribute in augmenting health care quality by fostering preventive medicine practices. We propose a solution to model patient trajectories that combines different types of information and considers the temporal aspect of clinical data. This solution leverages two different architectures: one supporting flexible sets of input features, to convert patient admissions into dense representations; and a second exploring extracted admission representations in a recurrent-based architecture, where patient trajectories are processed in sub-sequences using a sliding window mechanism. The developed solution was evaluated on two different clinical outcomes, unexpected patient readmission and disease progression, using the publicly available MIMIC-III clinical database. The results obtained demonstrate the potential of the first architecture to model readmission and diagnoses prediction using single patient admissions. While information from clinical text did not show the discriminative power observed in other existing works, this may be explained by the need to fine-tune the clinicalBERT model. Finally, we demonstrate the potential of the sequence-based architecture using a sliding window mechanism to represent the input data, attaining comparable performances to other existing solutions.

Automatic analysis of artistic paintings using information-based measures

The artistic community is increasingly relying on automatic computational analysis for authentication and classification of artistic paintings. In this paper, we identify hidden patterns and relationships present in artistic paintings by analysing their complexity, a measure that quantifies the sum of characteristics of an object. Specifically, we apply Normalized Compression (NC) and the Block Decomposition Method (BDM) to a dataset of 4,266 paintings from 91 authors and examine the potential of these information-based measures as descriptors of artistic paintings. Both measures consistently described the equivalent types of paintings, authors, and artistic movements. Moreover, combining the NC with a measure of the roughness of the paintings creates an efficient stylistic descriptor. Furthermore, by quantifying the local information of each painting, we define a fingerprint that describes critical information regarding the artists' style, their artistic influences, and shared techniques. More fundamentally, this information describes how each author typically composes and distributes the elements across the canvas and, therefore, how their work is perceived. Finally, we demonstrate that regional complexity and two-point height difference correlation function are useful auxiliary features that improve current methodologies in style and author classification of artistic paintings. The whole study is supported by an extensive website (http://panther.web.ua.pt) for fast author characterization and authentication.