Improving diabetic retinopathy screening using Artificial Intelligence: design, evaluation and before-and-after study of a custom development

Background: The worst outcomes of diabetic retinopathy (DR) can be prevented by implementing DR screening programs assisted by AI. At the University Hospital of Navarre (HUN), Spain, general practitioners (GPs) grade fundus images in an ongoing DR screening program, referring to a second screening level (ophthalmologist) target patients. Methods: After collecting their requirements, HUN decided to develop a custom AI tool, called NaIA-RD, to assist their GPs in DR screening. This paper introduces NaIA-RD, details its implementation, and highlights its unique combination of DR and retinal image quality grading in a single system. Its impact is measured in an unprecedented before-and-after study that compares 19,828 patients screened before NaIA-RD's implementation and 22,962 patients screened after. Results: NaIA-RD influenced the screening criteria of 3/4 GPs, increasing their sensitivity. Agreement between NaIA-RD and the GPs was high for non-referral proposals (94.6% or more), but lower and variable (from 23.4\% to 86.6%) for referral proposals. An ophthalmologist discarded a NaIA-RD error in most of contradicted referral proposals by labeling the 93% of a sample of them as referable. In an autonomous setup, NaIA-RD would have reduced the study visualization workload by 4.27 times without missing a single case of sight-threatening DR referred by a GP. Conclusion: DR screening was more effective when supported by NaIA-RD, which could be safely used to autonomously perform the first level of screening. This shows how AI devices, when seamlessly integrated into clinical workflows, can help improve clinical pathways in the long term.

Less can be more: representational vs. stereotypical gender bias in facial expression recognition

Machine learning models can inherit biases from their training data, leading to discriminatory or inaccurate predictions. This is particularly concerning with the increasing use of large, unsupervised datasets for training foundational models. Traditionally, demographic biases within these datasets have not been well-understood, limiting our ability to understand how they propagate to the models themselves. To address this issue, this paper investigates the propagation of demographic biases from datasets into machine learning models. We focus on the gender demographic component, analyzing two types of bias: representational and stereotypical. For our analysis, we consider the domain of facial expression recognition (FER), a field known to exhibit biases in most popular datasets. We use Affectnet, one of the largest FER datasets, as our baseline for carefully designing and generating subsets that incorporate varying strengths of both representational and stereotypical bias. Subsequently, we train several models on these biased subsets, evaluating their performance on a common test set to assess the propagation of bias into the models' predictions. Our results show that representational bias has a weaker impact than expected. Models exhibit a good generalization ability even in the absence of one gender in the training dataset. Conversely, stereotypical bias has a significantly stronger impact, primarily concentrated on the biased class, although it can also influence predictions for unbiased classes. These results highlight the need for a bias analysis that differentiates between types of bias, which is crucial for the development of effective bias mitigation strategies.

DSAP: Analyzing Bias Through Demographic Comparison of Datasets

In the last few years, Artificial Intelligence systems have become increasingly widespread. Unfortunately, these systems can share many biases with human decision-making, including demographic biases. Often, these biases can be traced back to the data used for training, where large uncurated datasets have become the norm. Despite our knowledge of these biases, we still lack general tools to detect and quantify them, as well as to compare the biases in different datasets. Thus, in this work, we propose DSAP (Demographic Similarity from Auxiliary Profiles), a two-step methodology for comparing the demographic composition of two datasets. DSAP can be deployed in three key applications: to detect and characterize demographic blind spots and bias issues across datasets, to measure dataset demographic bias in single datasets, and to measure dataset demographic shift in deployment scenarios. An essential feature of DSAP is its ability to robustly analyze datasets without explicit demographic labels, offering simplicity and interpretability for a wide range of situations. To show the usefulness of the proposed methodology, we consider the Facial Expression Recognition task, where demographic bias has previously been found. The three applications are studied over a set of twenty datasets with varying properties. The code is available at https://github.com/irisdominguez/DSAP.

Metrics for Dataset Demographic Bias: A Case Study on Facial Expression Recognition

Demographic biases in source datasets have been shown as one of the causes of unfairness and discrimination in the predictions of Machine Learning models. One of the most prominent types of demographic bias are statistical imbalances in the representation of demographic groups in the datasets. In this paper, we study the measurement of these biases by reviewing the existing metrics, including those that can be borrowed from other disciplines. We develop a taxonomy for the classification of these metrics, providing a practical guide for the selection of appropriate metrics. To illustrate the utility of our framework, and to further understand the practical characteristics of the metrics, we conduct a case study of 20 datasets used in Facial Emotion Recognition (FER), analyzing the biases present in them. Our experimental results show that many metrics are redundant and that a reduced subset of metrics may be sufficient to measure the amount of demographic bias. The paper provides valuable insights for researchers in AI and related fields to mitigate dataset bias and improve the fairness and accuracy of AI models. The code is available at https://github.com/irisdominguez/dataset_bias_metrics.

Multimodal Parameter-Efficient Few-Shot Class Incremental Learning

Few-Shot Class Incremental Learning (FSCIL) is a challenging continual learning task, where limited training examples are available during several learning sessions. To succeed in this task, it is necessary to avoid over-fitting new classes caused by biased distributions in the few-shot training sets. The general approach to address this issue involves enhancing the representational capability of a pre-defined backbone architecture by adding special modules for backward compatibility with older classes. However, this approach has not yet solved the dilemma of ensuring high classification accuracy over time while reducing the gap between the performance obtained on larger training sets and the smaller ones. In this work, we propose an alternative approach called Continual Parameter-Efficient CLIP (CPE-CLIP) to reduce the loss of information between different learning sessions. Instead of adapting additional modules to address information loss, we leverage the vast knowledge acquired by CLIP in large-scale pre-training and its effectiveness in generalizing to new concepts. Our approach is multimodal and parameter-efficient, relying on learnable prompts for both the language and vision encoders to enable transfer learning across sessions. We also introduce prompt regularization to improve performance and prevent forgetting. Our experimental results demonstrate that CPE-CLIP significantly improves FSCIL performance compared to state-of-the-art proposals while also drastically reducing the number of learnable parameters and training costs.

Gender Stereotyping Impact in Facial Expression Recognition

Facial Expression Recognition (FER) uses images of faces to identify the emotional state of users, allowing for a closer interaction between humans and autonomous systems. Unfortunately, as the images naturally integrate some demographic information, such as apparent age, gender, and race of the subject, these systems are prone to demographic bias issues. In recent years, machine learning-based models have become the most popular approach to FER. These models require training on large datasets of facial expression images, and their generalization capabilities are strongly related to the characteristics of the dataset. In publicly available FER datasets, apparent gender representation is usually mostly balanced, but their representation in the individual label is not, embedding social stereotypes into the datasets and generating a potential for harm. Although this type of bias has been overlooked so far, it is important to understand the impact it may have in the context of FER. To do so, we use a popular FER dataset, FER+, to generate derivative datasets with different amounts of stereotypical bias by altering the gender proportions of certain labels. We then proceed to measure the discrepancy between the performance of the models trained on these datasets for the apparent gender groups. We observe a discrepancy in the recognition of certain emotions between genders of up to $29 \%$ under the worst bias conditions. Our results also suggest a safety range for stereotypical bias in a dataset that does not appear to produce stereotypical bias in the resulting model. Our findings support the need for a thorough bias analysis of public datasets in problems like FER, where a global balance of demographic representation can still hide other types of bias that harm certain demographic groups.

Verification system based on long-range iris and Graph Siamese Neural Networks

Biometric systems represent valid solutions in tasks like user authentication and verification, since they are able to analyze physical and behavioural features with high precision. However, especially when physical biometrics are used, as is the case of iris recognition, they require specific hardware such as retina scanners, sensors, or HD cameras to achieve relevant results. At the same time, they require the users to be very close to the camera to extract high-resolution information. For this reason, in this work, we propose a novel approach that uses long-range (LR) distance images for implementing an iris verification system. More specifically, we present a novel methodology for converting LR iris images into graphs and then use Graph Siamese Neural Networks (GSNN) to predict whether two graphs belong to the same person. In this study, we not only describe this methodology but also evaluate how the spectral components of these images can be used for improving the graph extraction and the final classification task. Results demonstrate the suitability of this approach, encouraging the community to explore graph application in biometric systems.

Assessing Demographic Bias Transfer from Dataset to Model: A Case Study in Facial Expression Recognition

The increasing amount of applications of Artificial Intelligence (AI) has led researchers to study the social impact of these technologies and evaluate their fairness. Unfortunately, current fairness metrics are hard to apply in multi-class multi-demographic classification problems, such as Facial Expression Recognition (FER). We propose a new set of metrics to approach these problems. Of the three metrics proposed, two focus on the representational and stereotypical bias of the dataset, and the third one on the residual bias of the trained model. These metrics combined can potentially be used to study and compare diverse bias mitigation methods. We demonstrate the usefulness of the metrics by applying them to a FER problem based on the popular Affectnet dataset. Like many other datasets for FER, Affectnet is a large Internet-sourced dataset with 291,651 labeled images. Obtaining images from the Internet raises some concerns over the fairness of any system trained on this data and its ability to generalize properly to diverse populations. We first analyze the dataset and some variants, finding substantial racial bias and gender stereotypes. We then extract several subsets with different demographic properties and train a model on each one, observing the amount of residual bias in the different setups. We also provide a second analysis on a different dataset, FER+.

Generative Adversarial Networks for Bitcoin Data Augmentation

In Bitcoin entity classification, results are strongly conditioned by the ground-truth dataset, especially when applying supervised machine learning approaches. However, these ground-truth datasets are frequently affected by significant class imbalance as generally they contain much more information regarding legal services (Exchange, Gambling), than regarding services that may be related to illicit activities (Mixer, Service). Class imbalance increases the complexity of applying machine learning techniques and reduces the quality of classification results, especially for underrepresented, but critical classes. In this paper, we propose to address this problem by using Generative Adversarial Networks (GANs) for Bitcoin data augmentation as GANs recently have shown promising results in the domain of image classification. However, there is no "one-fits-all" GAN solution that works for every scenario. In fact, setting GAN training parameters is non-trivial and heavily affects the quality of the generated synthetic data. We therefore evaluate how GAN parameters such as the optimization function, the size of the dataset and the chosen batch size affect GAN implementation for one underrepresented entity class (Mining Pool) and demonstrate how a "good" GAN configuration can be obtained that achieves high similarity between synthetically generated and real Bitcoin address data. To the best of our knowledge, this is the first study presenting GANs as a valid tool for generating synthetic address data for data augmentation in Bitcoin entity classification.

Do we still need fuzzy classifiers for Small Data in the Era of Big Data?

The Era of Big Data has forced researchers to explore new distributed solutions for building fuzzy classifiers, which often introduce approximation errors or make strong assumptions to reduce computational and memory requirements. As a result, Big Data classifiers might be expected to be inferior to those designed for standard classification tasks (Small Data) in terms of accuracy and model complexity. To our knowledge, however, there is no empirical evidence to confirm such a conjecture yet. Here, we investigate the extent to which state-of-the-art fuzzy classifiers for Big Data sacrifice performance in favor of scalability. To this end, we carry out an empirical study that compares these classifiers with some of the best performing algorithms for Small Data. Assuming the latter were generally designed for maximizing performance without considering scalability issues, the results of this study provide some intuition around the tradeoff between performance and scalability achieved by current Big Data solutions. Our findings show that, although slightly inferior, Big Data classifiers are gradually catching up with state-of-the-art classifiers for Small data, suggesting that a unified learning algorithm for Big and Small Data might be possible.