Abstract:Decomposition of skin pigment plays an important role in medical fields. Human skin can be decomposed into two primitive components, hemoglobin and melanin. It is our goal to apply these results for diagnosis of skin cancer. In this paper, various methods for skin pigment decomposition are reviewed comparatively and the performance of each method is evaluated both theoretically and experimentally. In addition, isometric feature mapping (Isomap) is introduced in order to improve the dimensionality reduction performance in context of skin decomposition.
Abstract:We propose a new method to reconstruct data acquired in a local tomography setup. This method uses an initial reconstruction and refines it by correcting the low frequency artifacts known as the cupping effect. A basis of Gaussian functions is used to correct the initial reconstruction. The coefficients of this basis are iteratively optimized under the constraint of a known subregion. Using a coarse basis reduces the degrees of freedom of the problem while actually correcting the cupping effect. Simulations show that the known region constraint yields an unbiased reconstruction, in accordance to uniqueness theorems stated in local tomography.