LQ-Adapter: ViT-Adapter with Learnable Queries for Gallbladder Cancer Detection from Ultrasound Image

We focus on the problem of Gallbladder Cancer (GBC) detection from Ultrasound (US) images. The problem presents unique challenges to modern Deep Neural Network (DNN) techniques due to low image quality arising from noise, textures, and viewpoint variations. Tackling such challenges would necessitate precise localization performance by the DNN to identify the discerning features for the downstream malignancy prediction. While several techniques have been proposed in the recent years for the problem, all of these methods employ complex custom architectures. Inspired by the success of foundational models for natural image tasks, along with the use of adapters to fine-tune such models for the custom tasks, we investigate the merit of one such design, ViT-Adapter, for the GBC detection problem. We observe that ViT-Adapter relies predominantly on a primitive CNN-based spatial prior module to inject the localization information via cross-attention, which is inefficient for our problem due to the small pathology sizes, and variability in their appearances due to non-regular structure of the malignancy. In response, we propose, LQ-Adapter, a modified Adapter design for ViT, which improves localization information by leveraging learnable content queries over the basic spatial prior module. Our method surpasses existing approaches, enhancing the mean IoU (mIoU) scores by 5.4%, 5.8%, and 2.7% over ViT-Adapters, DINO, and FocalNet-DINO, respectively on the US image-based GBC detection dataset, and establishing a new state-of-the-art (SOTA). Additionally, we validate the applicability and effectiveness of LQ-Adapter on the Kvasir-Seg dataset for polyp detection from colonoscopy images. Superior performance of our design on this problem as well showcases its capability to handle diverse medical imaging tasks across different datasets. Code is released at https://github.com/ChetanMadan/LQ-Adapter

FocusMAE: Gallbladder Cancer Detection from Ultrasound Videos with Focused Masked Autoencoders

In recent years, automated Gallbladder Cancer (GBC) detection has gained the attention of researchers. Current state-of-the-art (SOTA) methodologies relying on ultrasound sonography (US) images exhibit limited generalization, emphasizing the need for transformative approaches. We observe that individual US frames may lack sufficient information to capture disease manifestation. This study advocates for a paradigm shift towards video-based GBC detection, leveraging the inherent advantages of spatiotemporal representations. Employing the Masked Autoencoder (MAE) for representation learning, we address shortcomings in conventional image-based methods. We propose a novel design called FocusMAE to systematically bias the selection of masking tokens from high-information regions, fostering a more refined representation of malignancy. Additionally, we contribute the most extensive US video dataset for GBC detection. We also note that, this is the first study on US video-based GBC detection. We validate the proposed methods on the curated dataset, and report a new state-of-the-art (SOTA) accuracy of 96.4% for the GBC detection problem, against an accuracy of 84% by current Image-based SOTA - GBCNet, and RadFormer, and 94.7% by Video-based SOTA - AdaMAE. We further demonstrate the generality of the proposed FocusMAE on a public CT-based Covid detection dataset, reporting an improvement in accuracy by 3.3% over current baselines. The source code and pretrained models are available at: https://gbc-iitd.github.io/focusmae