Using the Polar Transform for Efficient Deep Learning-Based Aorta Segmentation in CTA Images

Medical image segmentation often requires segmenting multiple elliptical objects on a single image. This includes, among other tasks, segmenting vessels such as the aorta in axial CTA slices. In this paper, we present a general approach to improving the semantic segmentation performance of neural networks in these tasks and validate our approach on the task of aorta segmentation. We use a cascade of two neural networks, where one performs a rough segmentation based on the U-Net architecture and the other performs the final segmentation on polar image transformations of the input. Connected component analysis of the rough segmentation is used to construct the polar transformations, and predictions on multiple transformations of the same image are fused using hysteresis thresholding. We show that this method improves aorta segmentation performance without requiring complex neural network architectures. In addition, we show that our approach improves robustness and pixel-level recall while achieving segmentation performance in line with the state of the art.

Self-Supervised Learning as a Means To Reduce the Need for Labeled Data in Medical Image Analysis

One of the largest problems in medical image processing is the lack of annotated data. Labeling medical images often requires highly trained experts and can be a time-consuming process. In this paper, we evaluate a method of reducing the need for labeled data in medical image object detection by using self-supervised neural network pretraining. We use a dataset of chest X-ray images with bounding box labels for 13 different classes of anomalies. The networks are pretrained on a percentage of the dataset without labels and then fine-tuned on the rest of the dataset. We show that it is possible to achieve similar performance to a fully supervised model in terms of mean average precision and accuracy with only 60\% of the labeled data. We also show that it is possible to increase the maximum performance of a fully-supervised model by adding a self-supervised pretraining step, and this effect can be observed with even a small amount of unlabeled data for pretraining.

A Survey of Left Atrial Appendage Segmentation and Analysis in 3D and 4D Medical Images

Atrial fibrillation (AF) is a cardiovascular disease identified as one of the main risk factors for stroke. The majority of strokes due to AF are caused by clots originating in the left atrial appendage (LAA). LAA occlusion is an effective procedure for reducing stroke risk. Planning the procedure using pre-procedural imaging and analysis has shown benefits. The analysis is commonly done by manually segmenting the appendage on 2D slices. Automatic LAA segmentation methods could save an expert's time and provide insightful 3D visualizations and accurate automatic measurements to aid in medical procedures. Several semi- and fully-automatic methods for segmenting the appendage have been proposed. This paper provides a review of automatic LAA segmentation methods on 3D and 4D medical images, including CT, MRI, and echocardiogram images. We classify methods into heuristic and model-based methods, as well as into semi- and fully-automatic methods. We summarize and compare the proposed methods, evaluate their effectiveness, and present current challenges in the field and approaches to overcome them.

Epicardial Adipose Tissue Segmentation from CT Images with A Semi-3D Neural Network

Epicardial adipose tissue is a type of adipose tissue located between the heart wall and a protective layer around the heart called the pericardium. The volume and thickness of epicardial adipose tissue are linked to various cardiovascular diseases. It is shown to be an independent cardiovascular disease risk factor. Fully automatic and reliable measurements of epicardial adipose tissue from CT scans could provide better disease risk assessment and enable the processing of large CT image data sets for a systemic epicardial adipose tissue study. This paper proposes a method for fully automatic semantic segmentation of epicardial adipose tissue from CT images using a deep neural network. The proposed network uses a U-Net-based architecture with slice depth information embedded in the input image to segment a pericardium region of interest, which is used to obtain an epicardial adipose tissue segmentation. Image augmentation is used to increase model robustness. Cross-validation of the proposed method yields a Dice score of 0.86 on the CT scans of 20 patients.