LLM-Orchestrated Conformance Checking in Stroke Care Without Computer-Interpretable Guidelines

Objective: Conformance checking in healthcare seeks to assess whether patient care pathways adhere to clinical guidelines. However, its practical application often depends on the availability of formal, machine-interpretable representations of guidelines, such as Computer-Interpretable Guidelines (CIGs), which are seldom available in real-world clinical settings. Methods: This work introduces a modular framework based on the orchestration of Large Language Models (LLMs) to support medical conformance checking directly from unstructured clinical and guideline texts, without requiring predefined CIGs. The proposed architecture integrates multiple LLMs and supporting components to extract patient traces from clinical discharge letters, identify normative rules from textual clinical guidelines, translate these rules into executable scripts, and compute a Trace Conformance Indicator to quantify compliance within the event log. Results: The framework was implemented and evaluated in the stroke care domain at the neurological ward of Alessandria Hospital. Hundreds of patient traces were automatically extracted from hospital data and assessed against 50 rules derived from the reference guideline. The analysis showed that more than 86\% of the available traces were conformant. Conclusion: The results demonstrate the feasibility of using orchestrated LLMs for practical healthcare conformance analysis. At the same time, the study provides evidence of a high level of adherence to stroke care guidelines at Alessandria Hospital.

Towards an educational tool for supporting neonatologists in the delivery room

Nowadays, there is evidence that several factors may increase the risk, for an infant, to require stabilisation or resuscitation manoeuvres at birth. However, this risk factors are not completely known, and a universally applicable model for predicting high-risk situations is not available yet. Considering both these limitations and the fact that the need for resuscitation at birth is a rare event, periodic training of the healthcare personnel responsible for newborn caring in the delivery room is mandatory. In this paper, we propose a machine learning approach for identifying risk factors and their impact on the birth event from real data, which can be used by personnel to progressively increase and update their knowledge. Our final goal will be the one of designing a user-friendly mobile application, able to improve the recognition rate and the planning of the appropriate interventions on high-risk patients.

Exploring Values in Museum Artifacts in the SPICE project: a Preliminary Study

This document describes the rationale, the implementation and a preliminary evaluation of a semantic reasoning tool developed in the EU H2020 SPICE project to enhance the diversity of perspectives experienced by museum visitors. The tool, called DEGARI 2.0 for values, relies on the commonsense reasoning framework TCL, and exploits an ontological model formalizingthe Haidt's theory of moral values to associate museum items with combined values and emotions. Within a museum exhibition, this tool can suggest cultural items that are associated not only with the values of already experienced or preferred objects, but also with novel items with different value stances, opening the visit experience to more inclusive interpretations of cultural content. The system has been preliminarily tested, in the context of the SPICE project, on the collection of the Hecht Museum of Haifa.

NRTS: A Client-Server architecture for supporting data recording, transmission and evaluation of multidisciplinary teams during the neonatal resuscitation simulation scenario

In this technical report, we describe Neonatal Resuscitation Training Simulator (NRTS), an Android mobile app designed to support medical experts to input, transmit and record data during a High-Fidelity Simulation course for neonatal resuscitation. This mobile app allows one to automatically send all the recorded data from "Neonatal Intensive Care Unit" (NICU) of Casale Monferrato Children's Hospital, (Italy) to a server located at the Department of Science and Technological Innovation (DiSIT), University of Piemonte Orientale (Italy). Finally, the medical instructor can view statistics on a simulation exercise that may be used during the de-briefing phase for the evaluation of multidisciplinary teams involved in the simulation scenarios.