The dynamics of the stomatognathic system from 4D multimodal data

The purpose of this chapter is to discuss methods of acquisition, visualization and analysis of the dynamics of a complex biomedical system, illustrated by the human stomatognathic system. The stomatognathic system consists of the teeth and the skull bones with the maxilla and the mandible. Its dynamics can be described by the change of mutual position of the lower/mandibular part versus the upper/maxillary one due to the physiological motion of opening, chewing and swallowing. In order to analyse the dynamics of the stomatognathic system its morphology and motion has to be digitized, which is done using static and dynamic multimodal imagery like CBCT and 3D scans data and temporal measurements of motion. The integration of multimodal data incorporates different direct and indirect methods of registration - aligning of all the data in the same coordinate system. The integrated sets of data form 4D multimodal data which can be further visualized, modeled, and subjected to multivariate time series analysis. Example results are shown. Although there is no direct method of imaging the TMJ motion, the integration of multimodal data forms an adequate tool. As medical imaging becomes ever more diverse and ever more accessible, organizing the imagery and measurements into unified, comprehensive records can deliver to the doctor the most information in the most accessible form, creating a new quality in data simulation, analysis and interpretation.

Band selection with Higher Order Multivariate Cumulants for small target detection in hyperspectral images

In the small target detection problem a pattern to be located is on the order of magnitude less numerous than other patterns present in the dataset. This applies both to the case of supervised detection, where the known template is expected to match in just a few areas and unsupervised anomaly detection, as anomalies are rare by definition. This problem is frequently related to the imaging applications, i.e. detection within the scene acquired by a camera. To maximize available data about the scene, hyperspectral cameras are used; at each pixel, they record spectral data in hundreds of narrow bands. The typical feature of hyperspectral imaging is that characteristic properties of target materials are visible in the small number of bands, where light of certain wavelength interacts with characteristic molecules. A target-independent band selection method based on statistical principles is a versatile tool for solving this problem in different practical applications. Combination of a regular background and a rare standing out anomaly will produce a distortion in the joint distribution of hyperspectral pixels. Higher Order Cumulants Tensors are a natural `window' into this distribution, allowing to measure properties and suggest candidate bands for removal. While there have been attempts at producing band selection algorithms based on the 3 rd cumulant's tensor i.e. the joint skewness, the literature lacks a systematic analysis of how the order of the cumulant tensor used affects effectiveness of band selection in detection applications. In this paper we present an analysis of a general algorithm for band selection based on higher order cumulants. We discuss its usability related to the observed breaking points in performance, depending both on method order and the desired number of bands. Finally we perform experiments and evaluate these methods in a hyperspectral detection scenario.