NeuroVoz: a Castillian Spanish corpus of parkinsonian speech

The advancement of Parkinson's Disease (PD) diagnosis through speech analysis is hindered by a notable lack of publicly available, diverse language datasets, limiting the reproducibility and further exploration of existing research. In response to this gap, we introduce a comprehensive corpus from 108 native Castilian Spanish speakers, comprising 55 healthy controls and 53 individuals diagnosed with PD, all of whom were under pharmacological treatment and recorded in their medication-optimized state. This unique dataset features a wide array of speech tasks, including sustained phonation of the five Spanish vowels, diadochokinetic tests, 16 listen-and-repeat utterances, and free monologues. The dataset emphasizes accuracy and reliability through specialist manual transcriptions of the listen-and-repeat tasks and utilizes Whisper for automated monologue transcriptions, making it the most complete public corpus of Parkinsonian speech, and the first in Castillian Spanish. NeuroVoz is composed by 2,903 audio recordings averaging $26.88 \pm 3.35$ recordings per participant, offering a substantial resource for the scientific exploration of PD's impact on speech. This dataset has already underpinned several studies, achieving a benchmark accuracy of 89% in PD speech pattern identification, indicating marked speech alterations attributable to PD. Despite these advances, the broader challenge of conducting a language-agnostic, cross-corpora analysis of Parkinsonian speech patterns remains an open area for future research. This contribution not only fills a critical void in PD speech analysis resources but also sets a new standard for the global research community in leveraging speech as a diagnostic tool for neurodegenerative diseases.

Artificial Intelligence applied to chest X-Ray images for the automatic detection of COVID-19. A thoughtful evaluation approach

Current standard protocols used in the clinic for diagnosing COVID-19 include molecular or antigen tests, generally complemented by a plain chest X-Ray. The combined analysis aims to reduce the significant number of false negatives of these tests, but also to provide complementary evidence about the presence and severity of the disease. However, the procedure is not free of errors, and the interpretation of the chest X-Ray is only restricted to radiologists due to its complexity. With the long term goal to provide new evidence for the diagnosis, this paper presents an evaluation of different methods based on a deep neural network. These are the first steps to develop an automatic COVID-19 diagnosis tool using chest X-Ray images, that would additionally differentiate between controls, pneumonia or COVID-19 groups. The paper describes the process followed to train a Convolutional Neural Network with a dataset of more than 79,500 X-Ray images compiled from different sources, including more than 8,500 COVID-19 examples. For the sake of evaluation and comparison of the models developed, three different experiments were carried out following three preprocessing schemes. The aim is to evaluate how preprocessing the data affects the results and improves its explainability. Likewise, a critical analysis is carried out about different variability issues that might compromise the system and the effects on the performance. With the employed methodology, a 91.5% classification accuracy is obtained, with a 87.4% average recall for the worst but most explainable experiment, which requires a previous automatic segmentation of the lungs region.