GroupMixer: Patch-based Group Convolutional Neural Network for Breast Cancer Detection from Histopathological Images

Diagnosis of breast cancer malignancy at the early stages is a crucial step for controlling its side effects. Histopathological analysis provides a unique opportunity for malignant breast cancer detection. However, such a task would be tedious and time-consuming for the histopathologists. Deep Neural Networks enable us to learn informative features directly from raw histopathological images without manual feature extraction. Although Convolutional Neural Networks (CNNs) have been the dominant architectures in the computer vision realm, Transformer-based architectures have shown promising results in different computer vision tasks. Although harnessing the capability of Transformer-based architectures for medical image analysis seems interesting, these architectures are large, have a significant number of trainable parameters, and require large datasets to be trained on, which are usually rare in the medical domain. It has been claimed and empirically proved that at least part of the superior performance of Transformer-based architectures in Computer Vision domain originates from patch embedding operation. In this paper, we borrowed the previously introduced idea of integrating a fully Convolutional Neural Network architecture with Patch Embedding operation and presented an efficient CNN architecture for breast cancer malignancy detection from histopathological images. Despite the number of parameters that is significantly smaller than other methods, the accuracy performance metrics achieved 97.65%, 98.92%, 99.21%, and 98.01% for 40x, 100x, 200x, and 400x magnifications respectively. We took a step forward and modified the architecture using Group Convolution and Channel Shuffling ideas and reduced the number of trainable parameters even more with a negligible decline in performance and achieved 95.42%, 98.16%, 96.05%, and 97.92% accuracy for the mentioned magnifications respectively.

A multi-channel framework for joint reconstruction of multi-contrast parallel MRI

Compressed sensing, multi-contrast and parallel imaging are all techniques that exploit certain types of redundancies to speed up image acquisition process and image quality in MRI. Although each individual category has been well developed, the combination of the three has not received significant attention, much less the potential benefit of isotropy within such a setting. In this paper, a novel isotropic multi-channel image regularizer is introduced, and its full potential is unleashed by integrating it into compressed multi-contrast multi-coil MRI.

Compressed MRI Reconstruction Exploiting a Rotation-Invariant Total Variation Discretization

Inspired by the first-order method of Malitsky and Pock, we propose a novel variational framework for compressed MR image reconstruction which introduces the application of a rotation-invariant discretization of total variation functional into MR imaging while exploiting BM3D frame as a sparsifying transform. The proposed model is presented as a constrained optimization problem, however, we do not use conventional ADMM-type algorithms designed for constrained problems to obtain a solution, but rather we tailor the linesearch-equipped method of Malitsky and Pock to our model, which was originally proposed for unconstrained problems. As attested by numerical experiments, this framework significantly outperforms various state-of-the-art algorithms from variational methods to adaptive and learning approaches and in particular, it eliminates the stagnating behavior of a previous work on BM3D-MRI which compromised the solution beyond a certain iteration.