Abstract:Cancer diagnoses typically involve human pathologists examining whole slide images (WSIs) of tissue section biopsies to identify tumor cells and their subtypes. However, artificial intelligence (AI)-based models, particularly weakly supervised approaches, have recently emerged as viable alternatives. Weakly supervised approaches often use image subsections or tiles as input, with the overall classification of the WSI based on attention scores assigned to each tile. However, this method overlooks the potential for false positives/negatives because tumors can be heterogeneous, with cancer and normal cells growing in patterns larger than a single tile. Such errors at the tile level could lead to misclassification at the tumor level. To address this limitation, we developed a novel deep learning pooling operator called CHARM (Contrastive Histopathology Attention Resolved Models). CHARM leverages the dependencies among single tiles within a WSI and imposes contextual constraints as prior knowledge to multiple instance learning models. We tested CHARM on the subtyping of non-small cell lung cancer (NSLC) and lymph node (LN) metastasis, and the results demonstrated its superiority over other state-of-the-art weakly supervised classification algorithms. Furthermore, CHARM facilitates interpretability by visualizing regions of attention.
Abstract:This report describes the methods employed by the Democritus University of Thrace (DUTH) team for participating in SemEval-2020 Task 11: Detection of Propaganda Techniques in News Articles. Our team dealt with Subtask 2: Technique Classification. We used shallow Natural Language Processing (NLP) preprocessing techniques to reduce the noise in the dataset, feature selection methods, and common supervised machine learning algorithms. Our final model is based on using the BERT system with entity mapping. To improve our model's accuracy, we mapped certain words into five distinct categories by employing word-classes and entity recognition.