In this paper, we present a multi-agent deep reinforcement learning (deep RL) framework for network slicing in a dynamic environment with multiple base stations and multiple users. In particular, we propose a novel deep RL framework with multiple actors and centralized critic (MACC) in which actors are implemented as pointer networks to fit the varying dimension of input. We evaluate the performance of the proposed deep RL algorithm via simulations to demonstrate its effectiveness. Subsequently, we develop a deep RL based jammer with limited prior information and limited power budget. The goal of the jammer is to minimize the transmission rates achieved with network slicing and thus degrade the network slicing agents' performance. We design a jammer with both listening and jamming phases and address jamming location optimization as well as jamming channel optimization via deep RL. We evaluate the jammer at the optimized location, generating interference attacks in the optimized set of channels by switching between the jamming phase and listening phase. We show that the proposed jammer can significantly reduce the victims' performance without direct feedback or prior knowledge on the network slicing policies. Finally, we devise a Nash-equilibrium-supervised policy ensemble mixed strategy profile for network slicing (as a defensive measure) and jamming. We evaluate the performance of the proposed policy ensemble algorithm by applying on the network slicing agents and the jammer agent in simulations to show its effectiveness.