Integrated sensing and communications (ISAC) has emerged as a pivotal enabling technology for next-generation wireless networks. Despite the distinct signal design requirements of sensing and communication (S&C) systems, shifting the symbol-wise pulse shaping (SWiPS) framework from communication-only systems to ISAC poses significant challenges in signal design and processing This paper addresses these challenges by examining the ambiguity function (AF) of the SWiPS ISAC signal and introducing a novel pulse shaping design for single-carrier ISAC transmission. We formulate optimization problems to minimize the average integrated sidelobe level (ISL) of the AF, as well as the weighted ISL (WISL) while satisfying inter-symbol interference (ISI), out-of-band emission (OOBE), and power constraints. Our contributions include establishing the relationship between the AFs of both the random data symbols and signaling pulses, analyzing the statistical characteristics of the AF, and developing algorithmic frameworks for pulse shaping optimization using successive convex approximation (SCA) and alternating direction method of multipliers (ADMM) approaches. Numerical results are provided to validate our theoretical analysis, which demonstrate significant performance improvements in the proposed SWiPS design compared to the root-raised cosine (RRC) pulse shaping for conventional communication systems.