Sensor configuration, including the sensor selections and their installation locations, serves a crucial role in autonomous driving. A well-designed sensor configuration significantly improves the performance upper bound of the perception system. However, as leveraging multiple sensors is becoming the mainstream setting, existing methods mainly focusing on single-sensor configuration problems are hardly utilized in practice. To tackle these issues, we propose a novel method based on conditional entropy in Bayesian theory to evaluate the sensor configurations containing both cameras and LiDARs. Correspondingly, an evaluation metric, perception entropy, is introduced to measure the difference between two configurations, which considers both the perception algorithm performance and the selections of the sensors. To the best of our knowledge, this is the first method to tackle the multi-sensor configuration problem for autonomous vehicles. The simulation results, extensive comparisons, and analysis all demonstrate the superior performance of our proposed approach.