This work studies the problems of channel estimation and beamforming for active reconfigurable intelligent surface~(RIS)-assisted communication, incorporating the mutual coupling~(MC) effect through an electromagnetically consistent model based on scattering parameters. We first demonstrate that MC can be incorporated into a compressed sensing~(CS) estimation formulation, albeit with an increase in the dimensionality of the sensing matrix. To overcome this increased complexity, we propose a two-stage strategy. Initially, a low-complexity MC-unaware CS estimation is performed to obtain a coarse channel estimate, which is then used to implement a dictionary reduction (DR) technique, effectively reducing the dimensionality of the sensing matrices. This method achieves low complexity comparable to the conventional MC-unaware approach while providing estimation accuracy close to that of the direct MC-aware CS method. We then consider the joint optimization of RIS configuration and base station (BS) combining in an uplink single-input multiple-output system. We employ an alternating optimization strategy where the BS combiner is derived in closed form for a given RIS configuration. The primary challenge lies in optimizing the RIS configuration, as the MC effect renders the problem non-convex and intractable. To address this, we propose a novel algorithm based on the successive convex approximation (SCA) and the Neumann series. Within the SCA framework, we propose a surrogate function that rigorously satisfies both convexity and equal-gradient conditions to update the iteration direction. Numerical results validate our proposal, demonstrating that the proposed channel estimation and beamforming methods effectively manage the MC in RIS, achieving higher spectral efficiency compared to state-of-the-art approaches.