Spacecraft trajectory design is a global search problem, where previous work has revealed specific solution structures that can be captured with data-driven methods. This paper explores two global search problems in the circular restricted three-body problem: hybrid cost function of minimum fuel/time-of-flight and transfers to energy-dependent invariant manifolds. These problems display a fundamental structure either in the optimal control profile or the use of dynamical structures. We build on our prior generative machine learning framework to apply diffusion models to learn the conditional probability distribution of the search problem and analyze the model's capability to capture these structures.