Frequency-domain learning draws attention due to its superior tradeoff between inference accuracy and input data size. Frequency-domain learning in 2D computer vision tasks has shown that 2D convolutional neural networks (CNN) have a stationary spectral bias towards low-frequency channels so that high-frequency channels can be pruned with no or little accuracy degradation. However, frequency-domain learning has not been studied in the context of 3D CNNs with 3D volumetric data. In this paper, we study frequency-domain learning for volumetric-based 3D data perception to reveal the spectral bias and the accuracy-input-data-size tradeoff of 3D CNNs. Our study finds that 3D CNNs are sensitive to a limited number of critical frequency channels, especially low-frequency channels. Experiment results show that frequency-domain learning can significantly reduce the size of volumetric-based 3D inputs (based on spectral bias) while achieving comparable accuracy with conventional spatial-domain learning approaches. Specifically, frequency-domain learning is able to reduce the input data size by 98% in 3D shape classification while limiting the average accuracy drop within 2%, and by 98% in the 3D point cloud semantic segmentation with a 1.48% mean-class accuracy improvement while limiting the mean-class IoU loss within 1.55%. Moreover, by learning from higher-resolution 3D data (i.e., 2x of the original image in the spatial domain), frequency-domain learning improves the mean-class accuracy and mean-class IoU by 3.04% and 0.63%, respectively, while achieving an 87.5% input data size reduction in 3D point cloud semantic segmentation.