Extractive reading comprehension systems are designed to locate the correct answer to a question within a given text. However, a persistent challenge lies in ensuring these models maintain high accuracy in answering questions while reliably recognizing unanswerable queries. Despite significant advances in large language models (LLMs) for reading comprehension, this issue remains critical, particularly as the length of supported contexts continues to expand. To address this challenge, we propose an innovative data augmentation methodology grounded in a multi-agent collaborative framework. Unlike traditional methods, such as the costly human annotation process required for datasets like SQuAD 2.0, our method autonomously generates evidence-based question-answer pairs and systematically constructs unanswerable questions. Using this methodology, we developed the FactGuard-Bench dataset, which comprises 25,220 examples of both answerable and unanswerable question scenarios, with context lengths ranging from 8K to 128K. Experimental evaluations conducted on seven popular LLMs reveal that even the most advanced models achieve only 61.79% overall accuracy. Furthermore, we emphasize the importance of a model's ability to reason about unanswerable questions to avoid generating plausible but incorrect answers. By implementing efficient data selection and generation within the multi-agent collaborative framework, our method significantly reduces the traditionally high costs associated with manual annotation and provides valuable insights for the training and optimization of LLMs.