This paper proposes a hybrid synthesis method for multi-exposure image fusion taken by hand-held cameras. Motions either due to the shaky camera or caused by dynamic scenes should be compensated before any content fusion. Any misalignment can easily cause blurring/ghosting artifacts in the fused result. Our hybrid method can deal with such motions and maintain the exposure information of each input effectively. In particular, the proposed method first applies optical flow for a coarse registration, which performs well with complex non-rigid motion but produces deformations at regions with missing correspondences. The absence of correspondences is due to the occlusions of scene parallax or the moving contents. To correct such error registration, we segment images into superpixels and identify problematic alignments based on each superpixel, which is further aligned by PatchMatch. The method combines the efficiency of optical flow and the accuracy of PatchMatch. After PatchMatch correction, we obtain a fully aligned image stack that facilitates a high-quality fusion that is free from blurring/ghosting artifacts. We compare our method with existing fusion algorithms on various challenging examples, including the static/dynamic, the indoor/outdoor and the daytime/nighttime scenes. Experiment results demonstrate the effectiveness and robustness of our method.