The task of Few-shot Learning (FSL) aims to do the inference on novel categories containing only few labeled examples, with the help of knowledge learned from base categories containing abundant labeled training samples. While there are numerous works into FSL task, Vision Transformers (ViTs) have rarely been taken as the backbone to FSL with few trials focusing on naive finetuning of whole backbone or classification layer.} Essentially, despite ViTs have been shown to enjoy comparable or even better performance on other vision tasks, it is still very nontrivial to efficiently finetune the ViTs in real-world FSL scenarios. To this end, we propose a novel efficient Transformer Tuning (eTT) method that facilitates finetuning ViTs in the FSL tasks. The key novelties come from the newly presented Attentive Prefix Tuning (APT) and Domain Residual Adapter (DRA) for the task and backbone tuning, individually. Specifically, in APT, the prefix is projected to new key and value pairs that are attached to each self-attention layer to provide the model with task-specific information. Moreover, we design the DRA in the form of learnable offset vectors to handle the potential domain gaps between base and novel data. To ensure the APT would not deviate from the initial task-specific information much, we further propose a novel prototypical regularization, which maximizes the similarity between the projected distribution of prefix and initial prototypes, regularizing the update procedure. Our method receives outstanding performance on the challenging Meta-Dataset. We conduct extensive experiments to show the efficacy of our model.