Robust Principal Component Analysis (RPCA) is a widely used method for recovering low-rank structure from data matrices corrupted by significant and sparse outliers. These corruptions may arise from occlusions, malicious tampering, or other causes for anomalies, and the joint identification of such corruptions with low-rank background is critical for process monitoring and diagnosis. However, existing RPCA methods and their extensions largely do not account for the underlying probabilistic distribution for the data matrices, which in many applications are known and can be highly non-Gaussian. We thus propose a new method called Robust Principal Component Analysis for Exponential Family distributions ($e^{\text{RPCA}}$), which can perform the desired decomposition into low-rank and sparse matrices when such a distribution falls within the exponential family. We present a novel alternating direction method of multiplier optimization algorithm for efficient $e^{\text{RPCA}}$ decomposition. The effectiveness of $e^{\text{RPCA}}$ is then demonstrated in two applications: the first for steel sheet defect detection, and the second for crime activity monitoring in the Atlanta metropolitan area.