Face presentation attack detection (PAD) plays a pivotal role in securing face recognition systems against spoofing attacks. Although great progress has been made in designing face PAD methods, developing a model that can generalize well to an unseen test domain remains a significant challenge. Moreover, due to different types of spoofing attacks, creating a dataset with a sufficient number of samples for training deep neural networks is a laborious task. This work addresses these challenges by creating synthetic data and introducing a deep learning-based unified framework for improving the generalization ability of the face PAD. In particular, synthetic data is generated by proposing a video distillation technique that blends a spatiotemporal warped image with a still image based on alpha compositing. Since the proposed synthetic samples can be generated by increasing different alpha weights, we train multiple classifiers by taking the advantage of a specific type of ensemble learning known as a stacked ensemble, where each such classifier becomes an expert in its own domain but a non-expert to others. Motivated by this, a meta-classifier is employed to learn from these experts collaboratively so that when developing an ensemble, they can leverage complementary information from each other to better tackle or be more useful for an unseen target domain. Experimental results using half total error rates (HTERs) on four PAD databases CASIA-MFSD (6.97 %), Replay-Attack (33.49%), MSU-MFSD (4.02%), and OULU-NPU (10.91%)) demonstrate the robustness of the method and open up new possibilities for advancing presentation attack detection using ensemble learning with large-scale synthetic data.